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doi: 10.3389/fphar.2023.1127634 Received 19 December 2022 Accepted 17 February 2023 Published 01 March 2023 Volume 14 - 2023 Edited by Daniel Hoyer, The University of Melbourne, Australia Reviewed by Hong-Ping Guan, Rezubio Pharmaceuticals Co., Ltd., China Sharon Cheetham, Syganture Discovery Ltd., United Kingdom Updates Copyright 2023 Medak, Weber, Shamshoum, McKie, Hahn and Wright

The lipopolysaccharide (LPS) endotoxin produced by gram-negative bacteria can trigger a strong immune response, and intraperitoneal injection of LPS in rodents serves as a classic model of systemic inflammation

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